Installing click once in different instances

Hi everyone,
I have some doubts about installing 2 different click once deployments over 2 instances. I already have one installed over an instancwe called "NAV", but I need to deploy another Click Once over the "DEMO" instance. Of course, both instances run in different ports, and they both have different certificates. The first time, I've installed ClickOnce with the script from the Azuer machine. But I'm afraid yo run the script again, and make the deployment against the same instace.
Should I change the script for using the DEMO instance in the deployment?

Thank you very much