Dynamics 365 for Finance and Operations

Now the On-Prem system requirements are available : https://www.microsoft.com/en-us/download/details.aspx?id=55496

To get it running the minimum recommended requirements are:

Total Number of instances(VM/Machines) : 21

Total number of CPU cores : 104

Total Memory : 408 Gb

This minimum configuration will estimated be able to support 240-1200 users.

To sum it up: Go Cloud . Much smarter.